<span style="font-weight: 400;">In vitro fertilization is one of the assisted reproductive technologies that has taken the medical world by storm. Cited as a boon of new-age technological advancements, IVF is a means of turning the dreams of numerous childless couples into a reality. IVF has been used more often as a first line of therapy for some causes of infertility in recent years due to its high success rate. So, what makes IVF unique and what are the statistics associated with it? This blog delves into the facts and figures surrounding IVF. Read ahead to know more.</span>

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<b>What is In Vitro Fertilization (IVF)?</b>

<span style="font-weight: 400;">The procedure of combining a woman’s egg with a man’s sperm in a petri dish under laboratory conditions is called in vitro fertilization (IVF). It involves a series of 5 basic steps as mentioned below:</span>
<ol>
 	<li><b>Stimulation/Super ovulation: </b><span style="font-weight: 400;">Using fertility drugs, several eggs are produced at a time instead of a single egg per month. This step requires a woman to undergo a few transvaginal ultrasounds and blood tests to check the hormone levels.</span></li>
 	<li><b>Egg retrieval:</b><span style="font-weight: 400;"> Through a minor surgery, called follicular aspiration, eggs are removed from the woman’s body. A thin needle is inserted through the vagina into the ovarian follicles. Now, using a suction device, the eggs, along with the fluid are taken out of each follicle, one at a time.</span></li>
 	<li><b>Insemination and fertilization:</b><span style="font-weight: 400;"> Mixing of the man’s sperm with the best quality eggs is called insemination. The fused egg and sperm are stored in an environmentally controlled chamber. Usually, the sperm enters or fertilizes the egg within a few hours after insemination. However, in cases where the chance of fertilization is low, the sperm is directly injected into the egg by means of intracytoplasmic sperm injection (ICSI).</span></li>
 	<li><b>Embryo culture:</b><span style="font-weight: 400;"> After 5 days of fertilization, the embryo develops into a blastocyst, which has several actively dividing cells. It is during this step that the embryo is screened for specific genetic disorders as well.</span></li>
 	<li><b>Embryo transfer:</b><span style="font-weight: 400;"> Embryos are placed into the woman’s womb 3 to 5 days after egg retrieval and fertilization. Using a thin tube called catheter, the embryos are introduced into the woman’s vagina, through the cervix, right up to the womb. If the embryo implants into the lining of the womb, pregnancy is said to take place.</span></li>
</ol>
<span style="font-weight: 400;"> </span>

<b>Conditions where IVF is used</b>

<span style="font-weight: 400;">In vitro fertilization is especially useful in the following conditions:</span>
<ul>
 	<li><span style="font-weight: 400;">       </span><span style="font-weight: 400;">Absence of fallopian tubes</span></li>
 	<li><span style="font-weight: 400;">       </span><span style="font-weight: 400;">Damaged or blocked fallopian tubes</span></li>
 	<li><span style="font-weight: 400;">       </span><span style="font-weight: 400;">Advanced age of woman (over 35 years)</span></li>
 	<li><span style="font-weight: 400;">       </span><span style="font-weight: 400;">Endometriosis</span></li>
 	<li><span style="font-weight: 400;">       </span><span style="font-weight: 400;">Male factor infertility</span>
<ul>
 	<li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;"> Azoospermia ( absence of sperms in ejaculate)</span></li>
 	<li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">Oligospermia (less than normal sperms in ejaculate)</span></li>
 	<li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">Erection or ejaculation problems</span></li>
</ul>


</li>
</ul>

<ul>
 	<li><span style="font-weight: 400;">       </span><span style="font-weight: 400;">Unexplained infertility</span></li>
</ul>
<span style="font-weight: 400;">.    Multiple cycles of failed ovulation induction/ IUI</span>
<h3></h3>
<b> </b>
<h3><b>The benefits and drawbacks of fresh and frozen embryo transfers</b></h3>
<img class="alignnone size-full wp-image-1142" src="https://www.nufertility.com/blog/wp-content/uploads/2024/02/3-min.jpg" alt="Embryo Transfer in Bangalore - NU Fertility" width="804" height="536" />

<b>Advantages of fresh embryo transfer</b>
<ul>
 	<li><span style="font-weight: 400;">   </span> <span style="font-weight: 400;">The waiting time for fresh embryo transfer is shorter as embryos are transferred soon after fertilization.</span></li>
 	<li><span style="font-weight: 400;">.  The embryo is not subjected to the stress of freezing and thawing.</span></li>
 	<li><span style="font-weight: 400;">   </span> <span style="font-weight: 400;">Fresh cycles involve the process of ovarian stimulation, which can result in a receptive endometrial lining, if the woman is not a hyper-responder. This, in turn, may enhance the chances of a successful embryo transfer.</span></li>
</ul>
<b>Disadvantages of fresh embryo transfer</b>
<ul>
 	<li><span style="font-weight: 400;">   </span> <span style="font-weight: 400;">Ovarian stimulation during fresh cycles may result in OHSS [Ovarian Hyperstimulation Syndrome], a potentially serious condition marked by enlarged and painful ovaries.</span></li>
 	<li><span style="font-weight: 400;">   </span> <span style="font-weight: 400;">Due to increased fertility medicines and extra hormones, the presence of higher-than-normal hormone levels in a patient's system can pose challenges for implantation when using their eggs.</span></li>
 	<li><span style="font-weight: 400;">   </span> <span style="font-weight: 400;">Fresh transfers are time-critical and need to be synchronized with the natural menstrual cycle, providing limited flexibility in terms of timing.</span></li>
</ul>
<span style="font-weight: 400;"> </span><b>Advantages of frozen embryo transfer</b>
<ul>
 	<li><span style="font-weight: 400;">   </span> <span style="font-weight: 400;">FET provides couples who have encountered challenging situations like cancer treatments with the opportunity to have children once their treatments are successfully completed.</span></li>
 	<li><span style="font-weight: 400;">  Women can plan pregnancy when they are ready for it. It provides flexibility in relation to planning the timing of embryo transfer</span></li>
 	<li><span style="font-weight: 400;">Reduced risk of Ovarian hyperstimulation syndrome.</span></li>
</ul>
&nbsp;

<b>Disadvantages of frozen embryo transfer</b>
<ul>
 	<li><span style="font-weight: 400;">   </span> <span style="font-weight: 400;">Not every embryo can withstand the freezing and thawing process, which could lead to a reduced number of embryos available for transfer.</span></li>
 	<li><span style="font-weight: 400;">   </span> <span style="font-weight: 400;">Going through frozen embryo transfer can be quite time-consuming.</span></li>
</ul>
<b> </b>

<b>Factors to consider when deciding between fresh or frozen embryo transfer</b>
<ol>
 	<li><b>Personal Health:</b><span style="font-weight: 400;"> If you have any health concerns, such as being at risk of OHSS, opting for frozen embryo transfer could be a safer choice for you.</span></li>
 	<li><b>Timing and Flexibility:</b><span style="font-weight: 400;"> Consider your own schedule, work obligations, and emotional preparedness for starting a family.</span></li>
 	<li><b>Success Rates:</b><span style="font-weight: 400;"> The success rates for both approaches are quite similar, but there are several factors that can influence the outcome, such as age, embryo quality, and medical history.</span></li>
</ol>
<span style="font-weight: 400;"> </span>

<span style="font-weight: 400;">The price range for </span><a href="https://www.nufertility.com/embryo-transfer"><span style="font-weight: 400;">embryo freezing in Bangalore</span></a><span style="font-weight: 400;"> is typically between Rs.20,000 and Rs.40,000. However, it is important to note that this pricing may vary across different hospitals and clinics. The decision to opt for fresh or frozen embryo transfer is a significant step in your fertility journey. It is important to consult your fertility specialist who can carefully assess your specific circumstances and help you determine the most suitable choice.</span> <span style="font-weight: 400;">Keep in mind that there isn't a one-size-fits-all solution, and your choice should align with your medical needs, emotional well-being, and your ultimate goal of starting a family. With the assistance of your healthcare team, you can make an informed decision for your path to parenthood.</span>

<a href="https://www.nufertility.com/"><span style="font-weight: 400;">NU Fertility in Bangalore</span></a><span style="font-weight: 400;"> provides advanced </span><a href="https://www.nufertility.com/fertility-preservation"><span style="font-weight: 400;">fertility preservation</span></a><span style="font-weight: 400;"> methods. Their dedicated healthcare team ensures exceptional care with precision and expertise in reproductive health. For specialized assistance with embryo transfer, reach out to NU Fertility.</span>

<span style="font-weight: 400;">Author: </span><a href="https://www.nufertility.com/dr-sneha-j"><span style="font-weight: 400;">Dr. Sneha J</span></a>
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